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Holiday Inn Wytheville 800-842-7652, 276-228-5483 1800 E. Main St., Wytheville, VA 24382 - pets, outdoor pool, restaurant within/nearby, interior and exterior corridors, 199 units, I-81/I-77, Exit 73 Home   Downtown History   Events  Attractions  Shopping  Outdoor Recreation  Wytheville Map  Wythe County Map  Camping  Accommodations   Restaurants     Mileage Map